Immunohistochemical study of the anatomical organization of the basal forebrain cholinergic system in the mouse brain
نویسندگان
چکیده
The anatomical organization of the basal forebrain cholinergic system with emphasis on the basal magnocellular nucleus, was studied by means of the choline acetyltransferase immunohistochemistry. The basal forebrain cholinergic system extends from the medial septum to the caudal part of the globus pallidus, and is organized as a continuous valley of cholinergic neurons. The arrangement of choline acetyltransferase immunopositive neurons, allows to distinguish four regions in the basal magnocellular nucleus: an anterior part from the horizontal limb of the diagonal band of Broca to the anterior commissure, an intermediate part between the anterior commissure and the globus pallidus, subdivided into dorsal and ventral regions, and a posterior part is found in the caudal globus pallidus, where cholinergic neurons are exclusively dorsal.
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